Significance of morphologic score and vascular index in the diagnosis of ovarian malignancy using ultrasonography.
- Author:
Jae Young LEE
1
;
So Jeong PARK
;
Ji No PARK
;
Da Rin KI
;
Ki Min KIM
;
Moon Kyoung JO
;
Chul Hong KIM
;
Seok Mo KIM
;
Ho Sun CHOI
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Chonnam National University, Gwangju, Korea. seokmo2001@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Morphologic score;
Resistance index;
Pulsatility index
- MeSH:
Diagnosis*;
Discrimination (Psychology);
Humans;
Laparoscopy;
Laparotomy;
Sensitivity and Specificity;
Ultrasonography*
- From:Korean Journal of Obstetrics and Gynecology
2006;49(6):1276-1284
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The aim of this study was to know whether we can distinguish benign from malignant ovarian tumors according to morphologic scoring system (MS), blood flow characteristics (Resistance index (RI), Pulsatility index (PI)) using color doppler sonography and a combination of both in patients undergoing laparotomy or laparoscopy for a clinically diagnosed ovarian mass. METHODS: From January 2001 to December 2003, 99 patients with ovarian tumors scheduled for laparotomy or laparoscopy were studied at our institute. Ultrasound was carried out to study the ovarian morphology followed by color doppler sonography. A score of > or =9 on MS, a PI< or =1 or a RI< or =0.4 was taken as suspicious for malignancy. RESULTS: A score of > or =9 on MS as indicative of malignancy was associated with the following statistical parameters: sensitivity 69.6%, specificity 69.8%, positive predictive value (PPV) 75.0%, negative predictive value (NPV) 63.8%. A mean score of malignant tumor (9.8+/-2.64) is significantly higher than that of benign tumor (7.5+/-2.44). This was statistically significant (p[t]<0.05). A resistance index (RI) < or =0.4 was associated with sensitivity 19.6%, specificity 97.6%, PPV 91.6%, NPV 48.2%. A pulsatility index (PI) < or =1.0 was associated with sensitivity 44.6%, specificity 81.3%, PPV 75.7%, NPV 53.0%. A mean of RI in malignancy (0.64+/-0.277) is lower than that of RI in benign tumor (0.79+/-0.299). A mean of PI in malignancy (1.34+/-0.982) is lower than that of PI in benign tumor (2.06+/-1.310). These was statistically significant (p[t]<0.05). The addition of RI or PI to MS did not improve the accuracy in predicting ovarian malignancy. CONCLUSION: Although RI or PI achieved better specificity and PPV compared to MS, the addition of RI or PI to MS did not increase its accuracy in the discrimination between benign and malignant ovarian tumors.
