Diagnostic value of 18F-FDG PET/CT in differentiating the cardiac benign from malignant lesions
10.3760/cma.j.issn.2095-2848.2015.02.002
- VernacularTitle:18F-FDG PET/CT在心脏占位性病变良恶性鉴别诊断中的应用
- Author:
Xiaoxin SUN
;
Zuoxiang HE
;
Xiaoli ZHANG
;
Wei FANG
;
Rui SHEN
;
Daoyu WANG
;
Yueqin TIAN
- Publication Type:Journal Article
- Keywords:
Heart neoplasms;
Tomography,emission-computed;
Tomography,X-ray computed;
Deoxyglucose
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2015;35(2):85-87
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical value of 18F-FDG PET/CT in differentiating between cardiac benign and malignant lesions.Methods From September 2009 to September 2012,a total of 9 (7males,2 females,average age (46± 22) years) patients with space-occupying lesions of the heart underwent whole body 18F-FDG PET/CT.18 F-FDG PET/CT diagnosis was made according to morphologic features and SUVmax of lesions.The final diagnoses were confirmed by either histopathology or clinical data and follow-up.Two-sample t test was used for data analysis.Results Among 9 cases of cardiac occupying lesions,4 cases were malignant tumors,4 cases were benign tumors (including 2 lipomas,1 myxoma,and 1 fibroma),1 case was thrombus.The average SUVmax of malignant tumors was 18.99±14.58,which was significantly higher than that of benign tumors (2.35±1.46,t=-2.58,P＜0.05).With a cut-off SUVmax of 4.6,18F-FDG PET/CT could be used to noninvasively detect malignant tumors with a sensitivity of 4/4,specificity of 4/5,and accuracy of 8/9.Only 1 thrombus was misdiagnosed.Conclusion 18F-FDG PET/CT can aid the noninvasive differential diagnosis of cardiac malignant tumors from benign lesions.
