Value of 18F-FDG PET/CT in the post-treatment evaluation of cervical cancer
10.3760/cma.j.issn.2095-2848.2015.03.002
- VernacularTitle:18F-FDG PET/CT显像在治疗后宫颈癌评估中的价值
- Author:
Feng CHEN
;
Tianzeng LIN
;
Chunjing YU
;
Xuyang YOU
;
Weixing WAN
- Publication Type:Journal Article
- Keywords:
Cervix neoplasms;
Neoplasm recurrence,local;
Neoplasm metastasis;
Tomography,emission-computed;
Tomography,X-ray computed;
Deoxyglucose
- From:
Chinese Journal of Nuclear Medicine and Molecular Imaging
2015;35(3):164-167
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of whole body 18F-FDG PET/CT in the detection of recurrence/metastasis of cervical cancer.Methods A retrospective study was performed on 95 patients with cervical cancer who underwent 18F-FDG PET/CT after treatment.The lesion characteristics on 18F-FDG PET/CT were assessed visually and semi-quantitatively.A final diagnosis was confirmed by histopathology,diagnostic treatment and clinical follow-up imaging.The data were analyzed by Kappa test.Results 18 F-FDG PET/CT was positive in 54 patients,including 24 with local recurrence and 30 with distant metastases.The sensitivity,specificity and accuracy of 18F-FDG PET/CT for the detection of recurrence/metastasis of cervical cancer were 98.1％ (52/53),95.2％ (40/42) and 96.8％ (92/95),respectively.The positive predictive and negative predictive value were 96.3％ (52/54) and 97.6％ (40/41),respectively.18F-FDG PET/CT showed concordant results with pathological/clinical follow-up findings (Kappa =0.936,P＜0.05).Conclusion 18F-FDG PET/CT is a sensitive and specific modality for the detection of recurrence/metastasis of cervical cancer and might be useful for further treatment plan.
