Surgery combined with albendazole liposomes for advanced hepatic alveolar echinococcosis
10.3760/cma.j.issn.1007-8118.2015.05.010
- VernacularTitle:手术联合阿苯达唑脂质体治疗晚期泡型肝包虫病
- Author:
Shunyun ZHAO
;
Yamin GUO
;
Bing LI
- Publication Type:Journal Article
- Keywords:
Advanced hepatic alveolar echinococcosis;
Surgery;
Albendazole liposomes
- From:
Chinese Journal of Hepatobiliary Surgery
2015;21(5):321-323
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the outcomes of surgery combined with albendazole liposomes in the treatment of advanced hepatic alveolar echinococcosis.Methods This is a retrospective study on 71 patients with advanced hepatic alveolar echinococcosis treated from January 2002 to November 2013.The patients were divided into 4 groups according to the surgical methods and whether surgery was combined with albendazole liposomes.Results On follow-up from 5 ～ 44 months,the mortality rates for the volume-reduction surgery group was 82.3％,the volume-reduction surgery + albendazole group 52.3％,the radical operation group 28.5％,and the radical operation + albendazole group 21.1％.The mortality rate of the radical operation + albendazole group,when compared with the radical operation group and the volume-reduction surgery + albendazole group was significantly different (P ＜ 0.05).The mortality rate of the radical operation group,when compared with the volume-reduction surgery + albendazole group showed no significant difference (P ＞ 0.05).The mortality rate of the volume-reduction surgery group,when compared with the volume-reduction surgery + albendazole group,the radical operation group,and the radical operation + albendazole group was significantly different (P ＜ 0.05).Conclusions The treatment of radical operation combined with albendazole liposomes for advanced hepatic alveolar echinococcosis reduced recurrence,improved quality of life and prolonged survival.It is a feasible method to treat these patients.
