Estimation of radiogenic cancer risk coefficients of stomach cancer in Chinese population
10.3760/cma.j.issn.0254-5098.2015.04.011
- VernacularTitle:我国人群辐射致胃癌危险系数估算研究
- Author:
Zhijuan SUN
;
Jixian WANG
;
Jian XIANG
;
Yongcheng ZHAO
;
Jingyun CHEN
;
Qingqing YANG
;
Saijun FAN
- Publication Type:Journal Article
- Keywords:
Excess risk of radiation carcinogen;
Risk transportation between populations;
Baseline of cancer incidence rate;
Stomach cancer
- From:
Chinese Journal of Radiological Medicine and Protection
2015;35(4):282-286
- CountryChina
- Language:Chinese
-
Abstract:
Objective To estimate the excess relative risk coefficients of stomach cancer for Chinese population attributable to ionizing radiation.Methods The excess relative risk and excess absolute risk coefficients of stomach cancer were estimated based on Life Span Study by using risk models developed by BEIR Ⅶ committee (Biological Effect of Ionizing Radiation).Guided by transportation methods from Life Span Study to Americans,we determined that transportation method for Chinese population includes both multiplicative and additive models with a weight of 0.7 and 0.3 respectively,on an arithmetic scale.Besides,curve fitting was used to obtain sex-age-specific stomach cancer baseline incidence based on Chinese cancer annual report.Then,Chinese excess relative risk coefficients of stomach cancer were obtained by substituting excess relative risk,excess absolute risk of Life Span Study and Chinese baseline incidence rate into risk transportation model.Results Excess relative risk coefficients of stomach cancer for Chinese population are 0.26/Sv for male and 0.64/Sv for female,whose exposure age is 30 years old and cancer age is 60 years old.Coefficients increase with decreased exposure age and cancer age.Conclusions Excess relative risk coefficients of stomach cancer for Chinese population are by larger higher than that of Life Span Study,and their sex-age tendency are similar.
