Myocardial involvement in patients with Takayasu arteritis
10.3760/cma.j.issn.1007-7480.2015.05.011
- VernacularTitle:大动脉炎并发心肌损害的临床特征分析
- Author:
Wenping PAN
;
Mengtao LI
;
Dong XU
;
Yong HOU
;
Xiaofeng ZENG
;
Fengchun ZHANG
- Publication Type:Journal Article
- Keywords:
Takayasu arteritis;
Cardiomyopathies;
Biomedical research
- From:
Chinese Journal of Rheumatology
2015;19(5):335-338
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical characteristics and related pathogenetic factors in Takayasu arteritis with myocardial involvement.Methods We retrospectively analyzed clinical data of Takayasu arteritis patients with myocardial involvement of Peking Union Medical College Hospital from 1987 to 2013.Results Myocardial involvement was diagnosed in 23 patients from 86 Takayasu arteritis patients.Sixty-five percent (15/23) of patients presented with congestive heart failure.Fifteen patients were without coronary artery involvement.Sixty-five percent (15/23) of patients with mild to moderate hypertension.Seventyfour percent(17/23) patients had pulmonary hypertension.Left ventricular ejection fraction was (34.70 ±0.09)％.Glucocorticco costeroid and immunosuppressive therapy could significantly increase left ventricular ejection fraction (t=4.302,P＜0.05).Conclusion We emphasize that myocardial involvement is common in Takayasu arteritis.It is an independent risk factor that impacts the prognosis.Early detection of myocardial involvement and effective therapy can improve the prognosis.
