Application of blood flow ratio indexes in diagnosis of Hashimoto thyroiditis different thyroid functions
10.3760/cma.j.issn.1004-4477.2015.03.014
- VernacularTitle:超声血流面积比技术对不同功能状态桥本甲状腺炎的应用研究
- Author:
Song BAI
;
Yujie LIU
;
Zhenzhen WANG
;
Jiawei TIAN
- Publication Type:Journal Article
- Keywords:
Ultrasonography;
Hashimoto diseases;
Thyroid function tests;
Blood flow ratio indexes
- From:
Chinese Journal of Ultrasonography
2015;24(3):223-227
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore application value of blood flow ratio indexes in the diagnosis of Hashimoto's thyroiditis(HT) with different thyroid functions.Methods One hundred and four patients who were diagnosed clinically as HT were enrolled in the study.The patients were classified into three groups according to thyroid functions:the hyperthyroidism group,the hypothyroidism group and the euthyroidism group.Thirty-two volunteers with normal thyroid functions were enrolled as control group.All the cases were examined with ultrasound and five blood flow ratio indexes were calculated automatically.Their differences in the four groups were compared.Results ①Among the five blood flow ratio indexes,three indexes(mean ratio,maxratio and minratio) had significant differences between each two groups(P ＜ 0.001),the other two indexes didn't have any differences among the four groups.②Two receiver operating characteristic (ROC) curves on meanratio were drew:a)HT with hyperthyroidism and HT with euthyroidism;b) HT with euthyroidism and HT with hypothyroidism.The cutoff value as a result of the ROC analysis of HT with hyperthyroidism and HT with euthyroidism was 0.235 with the maxim of specificity and sensitivity.The cutoff value of HT with euthyroidism and HT with hypothyroidism was 0.113 with the maxim of specificity and sensitivity.Both Bland-Altamn scatter diagrams and high intraclass correlation coefficient(ICC) showed that blood flow ratio indexes have high repeatability.Conclusions Blood flow ratio indexes are promising quantitative indexes in reflecting the vascularity of thyroid parenchyma,and they are helpful in the differential diagnosis of HT with different thyroid functions.
