Experimental study of evaluating left ventricular regional systolic function using speckle tracking echocardiography in acute myocardial infarction model of dogs: comparison of three-dimensional and two-dimensional approaches
10.3760/cma.j.issn.1004-4477.2014.10.024
- VernacularTitle:三维与二维斑点追踪技术评价急性心肌梗死犬左心室局部收缩功能的实验研究
- Author:
Ruifang ZHANG
;
Ge SONG
;
Huiruo LIU
;
Lina WU
;
Weitao GUO
;
Tingting HUO
;
Haiyan GUO
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Myocardial infarction;
Ventricular function,left;
Speckle tracking imaging
- From:
Chinese Journal of Ultrasonography
2014;23(10):902-906
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the value of three-dimensional speckle tracking imaging(3D-STI) in assessment of left ventricular regional systolic function in acute myocardial infarction model of dogs.Methods Left anterior descending (LAD) coronary artery was ligated in 24 adult beagle dogs.Longitudinal strain(LS) of every left ventricular segment before ligation and 180 min after ligation,and the time for acquisition and analysis were obtained using two-dimensional speckle tracking imaging (2D-STI) and 3D-STI.After the experiment,left ventricular myocardium were determined by TTC staining and divided into two groups:infarcted myocardial segments and non-infarcted myocardial segments.Results Experimental model of acute myocardial infarction was established successfully in 20 dogs.After ligation,both LS of 2D-STI and 3D-STI in infarcted myocardial segments were significantly lower (P ＜ 0.01).The time for acquisition and analysis of the images by 3D-STI were significantly shorter than that by 2D-STI (P ＜0.01).The area under the ROC curve of 3D-STI was larger than that of 2D-STI.A cut-off value of-12.56％ for LS of the 3D-STI had 77.9％ sensitivity and 88.2％ specificity in predicting acute myocardial infarction.Conclusions 3D-STI is a convenient,accurate method for evaluating left ventricular regional systolic function.
