Two cases report of autoimmune hemolytic anemia associated with acute kidney injury

VernacularTitle:急性肾损伤并自身免疫性溶血二例并文献复习
Author: Yunfang ZHANG ; Jian GUO ; Baojun HUA ; Jie LUO ; Hongyan LI
Publication Type:Journal Article
Keywords: Acute kidney injury; Autoimmune hemolysis; Anemia
From: Clinical Medicine of China 2014;30(12):1259-1261
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical characteristics of patients suffering from autoimmune hemolytic anemia(AIHA) associated with acute kidney injury (AKI).Methods The clinical data of 2 case patients with AIHA and AKI in the People's Hospital of Huadu District of Guangzhou was analyzed and associated literatures were reviewed.Results Two patients presented with severe anemia,raised reticulocyte count,positive Coomb's test,and acute renal failure.They were no effect therapy when treatment with agent of erythropoietin (EPO),iron or folic acid.The level of serum indirect bilirubin was at normal range.Liver function and serum LDH were normal too.However,treatment with corticosteroids was effective.Conclusion When patients suffering AKI occur worsening anemia,AIHA probably should be concerned.Treatment with corticosteroids early is effective.