Clinical curative effect observation of ultra pulse CO2 laser combined with collagen dressing in treatment of primary cutaneous amyloidosis
10.3760/cma.j.issn.1008-1372.2015.02.013
- VernacularTitle:超脉冲CO2激光联合胶原贴敷料治疗原发性皮肤淀粉样变临床疗效观察
- Author:
Bin YIN
;
Huanhuan SHI
;
Fan LI
;
Ping XU
;
Wei HU
- Publication Type:Journal Article
- Keywords:
Amyloidosis/TH;
Skin diseases/TH;
Lasers,gas/TU;
Collagen/AD
- From:
Journal of Chinese Physician
2015;17(2):202-204
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical efficacy and safety of ultra pulse CO2 laser combined with collagen dressing in treatment of cutaneous amyloidosis.Methods A total of 68 cases of primary cutaneous amyloidosis patients according to the different treatment methods was divided into two groups:the control group (n =33 cases) that was given acitretin capsules oral and topical compound flumetasone ointment packet treatment,and observation group (n =35 cases) with ultra pulse CO2 laser combined with collagen dressing external treatment.Two groups were observed in patients with curative effect and adverse reaction.Results Disease of integral observation group after treatment was significantly lower than the control group(t =3.12,P ＜0.05).The observation group had the efficiency of [88.6％ (31/35)] that was significantly higher than that of control group[17/33(51.5％),x2 =11.23,P ＜.0.01].The observation group had significantly shorter healing time [(5.38 ± 1.81) d] compared to the control group [(10.75 ±2.06)d,t =11.39,P ＜ 0.01].The observation group did not have recurrence,which was significantly different from the control group (x2 =4.90,P ＜ 0.05).Conclusions Ultra pulse CO2 laser combined with collagen dressing in treatment of primary cutaneous amyloidosis is a kind of effective treatment methods with remarkable curative effect and less adverse reactions.It is worthy of clinical application.
