Synthesis and biological properties of chlorosalicylamide derivatives
- Author:
Phuong Truong
- Publication Type:Journal Article
- Keywords:
chlorosalicylamide
- MeSH:
Drug Compounding;
chemical synthesis
- From:Pharmaceutical Journal
1998;265(5):8-12
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
4-chloroanilline, 5-chlorosalicylanilid and 3,5-dichlorosalicylic acid are obtained by chlorination aniline and salicylic acid in difference conditions. Condensation of the above compounds with aniline, salicylic acid and each other to get chlorosalicylanilid derivatives. Chlorosalicylanilid derivatives have high antibiotic and antifungal activity. All most of chlorosalicylanilid derivatives has low toxicity.
