A Long-Term Survival Case of a Primary Malignant Intracerebral Nerve Sheath Tumor.
10.3340/jkns.2013.54.3.261
- Author:
Byung Sun LEE
1
;
Young Gyu KIM
;
Dong Ho KIM
;
Mou Seop LEE
Author Information
1. Department of Neurosurgery, Chungbuk National University School of Medicine & Medical Research Institute, Cheongju, Korea. mslee@chungbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Malignant intracerebral nerve sheath tumor;
Gross total resection;
Radiotherapy;
Chemotherapy
- MeSH:
Drug Therapy;
Frontal Lobe;
Humans;
Prognosis;
Recurrence
- From:Journal of Korean Neurosurgical Society
2013;54(3):261-264
- CountryRepublic of Korea
- Language:English
-
Abstract:
We report a long-term survival case of a primary malignant intracerebral nerve sheath tumor (MINST) occurring in the right frontal lobe of a 13-year old boy. After the gross total resection (GTR), we have performed radiation therapy but it recurred 50 months after the surgery, so the second GTR was performed. Later, second tumor recurrence was found 4 months after the second surgery. Subsequently the third GTR, radiotherapy, and chemotherapy were carried out. At present, the patient has been remaining alive for 77 months without evidence of tumor recurrence. According to the previous reports, the primary MINST is very rare : there are only 8 cases reported. It is also a fast-growing, invasive tumor with poor outcome. This is the first case that had no recurrence for 50 months after the surgery among the reported cases that had been followed up for more than 5 years. It is supposed that a period of recurrence free survival after GTR and low mitotic activity are associated with the patient's prognosis. A GTR followed by adjuvant radiation therapy and chemotherapy will be recommended to patients of MINST.
