The role of cathepsin G in the diagnosis and immunotherapy of acute myeloid leukemia
10.3760/cma.j.issn.1009-9921.2015.03.017
- VernacularTitle:组织蛋白酶G在急性髓系白血病诊断及免疫治疗中的作用
- Author:
Mingli YANG
- Publication Type:Journal Article
- Keywords:
Cathepsin G;
Acute myeloid leukemia;
Immunotherapy
- From:
Journal of Leukemia & Lymphoma
2015;24(3):190-192
- CountryChina
- Language:Chinese
-
Abstract:
Cathepsin G (CG) is one of the serine proteases of neutrophils,and its mRNA is specifically increased in the promyelomonocytic stage of neutrophils and abnormal in several acute myeloid leukemias (AML).Meanwhile,CG is one of AML-associated antigens with strong immunocompetence,it is an important target of immunotherapy in AML.In this paper,the role of CG in the diagnosis and immunotherapy of AML were reviewed.
