Iron homeostasis and diagnosis of hereditary iron overload: reports from the 56th American Society of Hematology annual meeting
10.3760/cma.j.issn.1009-9921.2015.01.014
- VernacularTitle:铁稳态和遗传性铁过载的诊断:第56届美国血液学会年会报道
- Author:
Xudong TANG
;
Lu ZHANG
;
Feng LIU
- Publication Type:Journal Article
- Keywords:
Iron overload;
American Society of Hematology annual meeting
- From:
Journal of Leukemia & Lymphoma
2015;24(1):46-49
- CountryChina
- Language:Chinese
-
Abstract:
The research progresses of iron homeostasis and the diagnosis of hereditary iron overload in the 56th American Society of Hematology (ASH) annual meetings were reviewed.Over the last 2 decades,the discovery of mutations in genes leading to hereditary disorders of iron overload,iron deficiency,and iron maldistribution had accelerated our understanding of human iron homeostasis.This article provided an updated overview of the human iron cycle,regulation of iron homeostasis,how perturbations in these homeostatic mechanisms led to iron overload disease and strategies for the diagnosis of hereditary iron overload.
