Effect of aescine sodium combined with albumin treatment in hypertensive cerebral hemorrhage after minimally invasive scavenging surgery
10.3760/cma.j.issn.1008-6706.2015.01.014
- VernacularTitle:七叶皂苷钠联合人血白蛋白在高血压脑出血微创清除术后的应用效果
- Author:
Tao PAN
;
Dujuan SHA
;
Peng XU
;
Qiming LI
;
Jun ZHANG
;
Guofeng FAN
- Publication Type:Journal Article
- Keywords:
Cerebral Hemorrhage;
Hematoma;
Aescine sodium;
Albumins
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;22(1):41-44
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of aescine sodium combined with albumin in the treatment of hypertensive intracerebral hemorrhage after intracranial hematoma minimally invasive removal surgery.Methods 50 patients with hypertensive intracerebral hemorrhage after intracranial hematoma minimally invasive removal surgery were randomly divided into the two groups:the treatment group was treated with aescine sodium and albumin,the control group was treated with the conventional medical drugs;The neural function defect scale,brain edema area of postoperative patients after 1d and 15d,clinical effects after 15d were observed.Results 15d after operation,in the treatment group,the brain edema area was (2.40 ± 0.32) cm2,neural function defect scale was (9.44 ± 2.25) points,which were better than (3.40 ±0.85) cm2 (t =4.721,P ＜0.01) and (15.65 ±3.04) points(t =3.625,P ＜0.01).The total effective rate of the treatment group was 88.9％,which was better than 69.6％ of the control group(x2 =13.58,P ＜0.01).Conclusion Aescine sodium combined with albumin can effectively reduce perihematomal brain edema area,improve nerve function defect and clinical effect in the patients with hypertensive cerebral hemorrhage after minimally invasive scavenging surgery.
