Temperature instability of Prader-Willi syndrome in an infant
10.3969/j.issn.1000-3606.2015.04.018
- VernacularTitle:Prader-Willi综合征体温不稳定1例报告
- Author:
Ying FENG
;
Nong XIAO
;
Yuxia CHEN
- Publication Type:Journal Article
- Keywords:
Prader-Willi syndrome;
temperature instability;
fever
- From:
Journal of Clinical Pediatrics
2015;(4):361-363
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo study the clinical characteristics of the temperature instability in Prader-Willi syndrome (PWS). MethodsThe clinical characteristics of one case of PWS with recurrent fever were retrospectively analyzed.ResultsA 5-month-old boy who had such clinical characteristics as low central muscle tension, sucking weakness, feeding dififculties, cryptorchidism and white skin was diagnosed as PWS by chromosomal microarray analysis and methylation-speciifc PCR. In the course of the disease, the infant presented recurrent fever. The pathogenic bacteria culture and virus antibody detection showed negative, and the treatment of reducing fever, anti-infection and immune support were ineffective.ConclusionsThe cause of the recurrent fever is unknown and central fever is suspected. Whether the temperature instability is the clinical feature of PWS still needs a lot of clinical researches.
