Advance of drug-resistant epilepsy's definition and its application
10.3760/cma.j.issn.2095-428X.2015.07.024
- VernacularTitle:耐药性癫(癎)的定义及其应用进展
- Author:
Yong WU
;
Jianxiang LIAO
- Publication Type:Journal Article
- Keywords:
Drug-resistant;
Refractory;
Epilepsy;
International League Against Epilepsy
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;30(7):558-560
- CountryChina
- Language:Chinese
-
Abstract:
In the use of antiepileptic drugs in patients with epilepsy,1/3 of the patients with epilepsy can not get effective control,showing resistance to antiepileptic drugs.Now the mechanism of drug resistance is considered to be caused by multiple factors work together.The concept and connotation between drug-resistant epilepsy and refractory epilepsy are different.Since 2010,the international union of antiepileptic proposeddrug-resistant epilepsy expert consensus,different medical centers use the new defition to study different populations and confirm that the new definition is effective and reliable.However,there are some controversier about the drug dosage,drug kinds,judge for determining evaluation index and the treatment judgement in that definition.
