Sclerosing mesenteritis associated with skin panniculitis and pleural thickening.
- Author:
Kyoung Ha PARK
1
;
Hyun Kyu CHANG
;
Sun Young CHOI
;
Myoung Sik HAN
;
Youn Baik CHOI
;
Nam Hyeon KIM
;
Haingsub R CHUNG
;
Hwan HERR
Author Information
1. Department of Internal Medicine, Asan-Fundation Kangnung Hospital, Kangung, Korea.
- Publication Type:Case Report
- Keywords:
Sclerosing mesenreritis;
Skin panniculitis;
Pleural thickening
- MeSH:
Abdominal Pain;
Biopsy;
Cyclophosphamide;
Fat Necrosis;
Fibrosis;
Humans;
Inflammation;
Middle Aged;
Panniculitis*;
Panniculitis, Peritoneal*;
Prednisolone;
Prednisone;
Rare Diseases;
Skin*;
Weight Loss
- From:Korean Journal of Medicine
1999;57(1):103-107
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sclerosinng mesenteritis is a rare disease that occurs most often among middle aged man. Fewer than 200 cases have been reported in the literature. It is a benign mesenteric lesion characterized by fat necrosis, fibrosis and chronic inflammation. The pathogenesis of this disease is unclear through an autoimmune origin has been proposed. The disease is generally localized and self- limiting. Fatal case is rare but has been reported. In patients with biopsy proven sclerosing mesenteritis having a relentless downhill course, treatment with prednisolone and oral cyclophosphamide in isolated case report has lead to evident clinical and radiological responses. This is a report of a case of sclerosing mesenteritis, who presented to us with history of colicky abdominal pain and weight loss. She was treated with prednisone and intravenous cyclophosphamide pulse therapy and resulted in radiological and clinical improvement. Interestingly this case has associated with skin panniculitis and pleural thickening. The skin panniculitis also showed good response to prednisolone. Our case is the first in which sclerosing mesenteritis was associated with pleural thickening.
