Medical polyethylene glycol berberinevia shoulder joint injections for the treatment of subacromial impingement syndrome：a follow-up of 6 months
10.3969/j.issn.2095-4344.2015.12.016
- VernacularTitle:医用聚乙二醇小檗碱肩关节注射修复肩峰下撞击综合征：6个月随访
- Author:
Liqin WANG
;
Suohua PAN
;
Yueying CHEN
;
Jun WU
- Publication Type:Journal Article
- Keywords:
Polyethylene Glycols;
Berberine;
Shoulder Impingement Syndrome
- From:
Chinese Journal of Tissue Engineering Research
2015;(12):1889-1893
- CountryChina
- Language:Chinese
-
Abstract:
BACKGROUND:Medical polyethylene glycol berberine is a biomaterial against tissue adhesion, with anti-inflammatory effects, which can prevent scar formation and reduce local inflammation. OBJECTIVE:To observe the clinical efficacy of medical polyethylene glycol berberinevia shoulder joint injections on subacromial impingement syndrome. METHODS:Forty patients with subacromial impingement syndrome I, II were voluntarily divided into two groups: biomaterial group (n=20), single intra-articular injection of 3 mL medical polyethylene glycol berberine; conservative treatment group (n=20), single subacromial space closed treatment of betamethasone combined with lidocaine hydrochloride folowed by oral administration of celecoxib 200 mg once, twice a day, totaly for 1 week. Patients were folowed up clinicaly for visual analog scale scores, range of motion of the shoulder and the American Shoulder and Elbow Surgeons scores. RESULTS AND CONCLUSION:Both of two groups had a great improvement in visual analog scale scores, range of motion of the shoulder and the American Shoulder and Elbow Surgeons scores after treatment (P< 0.05), and these scores were improved more significantly in the biomaterial group than the conservative treatment group at 2 weeks, 4 weeks, 3 months, 6 months after treatment (P < 0.001). These findings indicate that the intra-articular injection of medical polyethylene glycol berberine for subacromial impingement syndrome can effectively aleviate shoulder pain, improve shoulder mobility, and promote functional recovery of the shoulder.
