A case of aplastic anemia after habitual sniffing of glue and volatile substances.
- Author:
Deog Ho KWON
1
;
Sang Yong JUNG
;
Jin Hee KIM
;
Jong Ik JUNG
;
Dong Woo SHIN
;
Jung Hyun CHUN
;
Jae Wook SHIN
;
Jung Ah KWON
;
Tae Eui SONG
Author Information
1. Department of Internal Medicine, Seoul Red Cross Hospital, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Aplastic anemia;
Glue sniffing;
Toluene;
Xylene
- MeSH:
Adhesives*;
Adolescent;
Anemia, Aplastic*;
Benzene;
Biopsy;
Blood Platelets;
Bone Marrow;
Flavin-Adenine Dinucleotide;
Gingiva;
Hematocrit;
Hemorrhage;
Humans;
Inhalant Abuse;
Inhalation;
Kidney;
Liver;
Male;
Nervous System;
Solvents;
Toluene;
Xylenes;
Young Adult
- From:Korean Journal of Medicine
1999;57(1):118-121
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The inhalation of volatile substances has becoming a popular fad among adolescents in the world. Glue sniffing is associated with injury of nervous system, liver and kidney. And rarely abnormality of blood and bone marrow suppression can develop. The main components of volatile substances that cause hematologic abnormality is thought to be benzene, toluene, and xylene. A 24 year-old male was admitted to our hospital due to gum bleeding. He was a chronic glue and organic solvents sniffer for 6 years, and quit sniffing 1 year before admission. He had no specific drug history. On admission, CBC was as follows: WBC 2,500/mm3; hemoglobin 8.9g/dl; hematocrit 25.1%; platelet 2,000/mm3. Bone marrow biopsy showed severe hypocellular marrow compatible with aplastic anemia. We report a case of aplastic anemia after habitual sniffing of glue and volatile substances with brief review of the literature.
