Stent thrombosis and major clinical events after BuMA coronary stent implantation
10.11958/j.issn.0253-9896.2015.04.024
- VernacularTitle:国产BuMA支架术后支架血栓及主要临床事件随访分析
- Author:
Kui HUANG
;
Weiwei YU
;
Weiying LYU
;
Yin LIU
- Publication Type:Journal Article
- Keywords:
drug-eluting stents;
coronary disease;
coronary angiography;
angioplasty,transluminal,percutaneous coro-nary;
stent thrombosis
- From:
Tianjin Medical Journal
2015;(4):422-425
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the long-term safety and efficacy of the domestic biodegradable drug-eluting cor?onary stents (BuMA) in treating coronary heart disease (CHD). Methods Patients (n=440) who received BUMA stents were designated as observation group while patients (n=460) received Resolutestents were designated as control group. The base?line clinical characteristics, extend of pathological change shown by Coronary Arteriography (CAG),the procedure of percu?taneous coronary intervention were similar between these two groups. The patients were followed up for a mean of 24 ± 4 months;the primary endpoint was the occurrence of definite or probable stent thrombosis;secondary endpoint was major ad?verse cardiac events (MACEs) including complex end such as recurrent angina, acute non-fatal myocardial infarction, death, target vessel revascularization (TVR); other endpoints include all- cause mortality, cardiac death, myocardial infarc?tion (MI), target lesion revascularization (TLR), non-target vessel revascularization and stroke. Some patients were lost dur?ing follow up, which include 5 in observation group and 26 in control group. Results Patients in observation groups were in?serted with 615 stents while patients in control group were implanted with 614 stents, both groups with average of implanting 1.41 stent/case. There are no statistical significance differences in the primary endpoint [1.4%(6/435) vs 1.8%(8/434), χ2=0.087], secondary endpoint [12.3%(54/435) vs 10.8%(47/434),χ2=0.524] and other endpoints between the two groups. Con?clusion These data suggest that domestic biodegradable drug-eluting coronary stents (BuMA) are with good long-term safe?ty and efficacy.
