Effect of different analgesia methods on blood coagulation in pa-tients who underwent esophageal carcinoma surgery
10.3969/j.issn.1000-8179.20150117
- VernacularTitle:不同镇痛方式对食管癌根治术后患者凝血功能的影响
- Author:
Yuanyuan LIU
;
Ping WANG
- Publication Type:Journal Article
- Keywords:
patient-controlled epidural analgesia;
patient-controlled intravenous analgesia;
esophageal neoplasm;
thrombelastogra-phy;
coagulation
- From:
Chinese Journal of Clinical Oncology
2015;(7):378-381
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effect of different analgesia methods on blood coagulation in patients who underwent esophageal carcinoma surgery through thrombelastography (TEG). Methods:A total of 60 patients who underwent radical esophagecto-my were randomly divided into the patient-controlled epidural analgesia (PCEA) group and patient-controlled intravenous analgesia (PCIA) group with 30 cases each. The visual analogue scale (VAS) and patient-controlled analgesia (PCA) bottom pressing times were recorded at 6, 12, 24, and 48 h after surgery. The TEG parameters were measured at the time before anesthesia (T0), the end of surgery (T1), first day after operation (T2), second day after operation (T3), and third day after operation (T4). Results:(1) Compared with the PCIA group, the VAS scores and PCA bottom pressing times were significantly lower (P<0.05). (2) The R and K values of the PCEA group had no significant difference compared with T0 (P>0.05), and were significantly prolonged than those in the PCIA group at T2, T3, and T4 (P<0.05). (3) The platelet amount of the two groups decreased at T2 and T3 compared with that at T0 (P<0.05). Conclu-sion:The analgesic effect of PCEA was better than that of PCIA in patients who underwent esophageal carcinoma surgery, and may im-prove their hypercoagulability.
