Relationship between plasma homocysteine level and carotid atherosclerosis in H-hypertensive patients
10.3969/j.issn.1673-4130.2015.07.022
- VernacularTitle:H 型高血压患者血浆同型半胱氨酸水平与颈动脉粥样硬化的关系
- Author:
Xiaoling LIU
;
Juexin MA
- Publication Type:Journal Article
- Keywords:
H hypertension;
homocysteine;
carotid atherosclerosis
- From:
International Journal of Laboratory Medicine
2015;(7):915-917
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between the plasma homocysteine(Hcy)level and carotid atherosclerosis in the patients with H hypertension .Methods 200 patients with essential hypertension were divided into the research group (complicating homocysteinemia) and the control group according to whether complicating homocysteinemia .Carotid artery was detected and its average intima‐media thickness (IMT) was measured for all the patients by GE LOGIQ3 type color Doppler ultrasonograph .Simul‐taneously ,the levels of plasma Hcy ,triglycerides ,total cholesterol ,high‐density lipoprotein cholesterol and low density lipoprotein cholesterol were detected .Results Average carotid IMT in the research group was significantly higher than that in the control group(P<0 .05) ,and with the increase of the Hcy level ,IM T was gradually thickened ;in addition ,the atherosclerosis degree of ca‐rotid artery was significantly associated with the Hcy level (P<0 .05) .Conclusion The Hcy level is closely related with the ather‐osclerosis degree of carotid artery in the patients with H hypertension .
