Effect of different pancreaticojejunal anastomoses on the occur-rence of pancreatic fistula after pancreaticoduodenectomy
10.3969/j.issn.1000-8179.20150123
- VernacularTitle:胰肠吻合方式对胰十二指肠切除术后胰瘘的影响
- Author:
Jiafei HUANG
;
Ti ZHANG
;
Hongyuan ZHOU
;
Huikai LI
;
Yunlong CUI
;
Qiang LI
- Publication Type:Journal Article
- Keywords:
pancreaticoduodenectomy;
pancreaticojejunostomy;
pancreatic fistula
- From:
Chinese Journal of Clinical Oncology
2015;42(8):441-445
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the effect of pancreaticojejunostomy on the occurrence of postoperative pancreatic fistula (POPF) after pancreaticoduodenectomy. Methods:Data from 145 patients with periampullary tumor who underwent pancreaticoduode-nectomy in Tianjin Medical University Cancer Institute and Hospital between October 2008 and August 2013 were reviewed. Factors potentially associated with POPF were analyzed by Pearson chi-square test and Logistic regression analysis. Results:Among the 145 patients, 27 were diagnosed with POPF, including 5 grade A, 17 grade B and 5 grade C. Neither duct to mucosa nor Blumgart pancreati-cojejunostomy was correlated with POPF in grade C. The univariate analysis showed that gender, pancreatic cancer, portal vein involve-ment, type of pancreaticojejunostomy, texture of pancreas, and diameter of the main pancreatic duct were closely correlated with POPF. The multivariate analysis using Logistic regression showed that different pancreaticojejunal anastomoses and genders were independent predictors of POPF. Conclusion:Different types of pancreatic anastomoses are a risk factor for POPF after pancreaticoduodenectomy.