Three kinds of double-J ureteral stents: a comparison of biocompatibility
10.3969/j.issn.2095-4344.2015.16.027
- VernacularTitle:三种类型双J输尿管支架的生物相容性比较
- Author:
Yinhua YU
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2015;19(16):2603-2607
- CountryChina
- Language:Chinese
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Abstract:
BACKGROUND:Ureteral stents used in clinical treatment are mostly made of silicone or polyurethane polymer materials, but these materials cannot be degraded and absorbed in the human body. Therefore, to develop a new type of double-J biodegradable ureteral stent has become a research focus. OBJECTIVE:To summarize the clinical application and development of different kinds of double-J ureteral stents. METHODS: Related literatures were retrieved from Wanfang, CNKI and PubMed databases using the keywords of double-J ureteral, stent, clinical in Chinese and English, respectively. The retrieval time ranged from 2010 to 2015. RESULTS AND CONCLUSION:Traditional double-J Ureteral stents can be divided into polymer stents and metal stents, both of which have poor biocompatibility and easily cause various complications. With the in-depth studies of ureteral stents, biodegradable ureteral stents have been developed, which have good mechanical properties, biological inertness and in vivo degradation that can ensure drainage of urine after implantation in the human body without affecting the dynamics of the upper urinary tract; have good histocompatibility, little reactions between tissues, and can disappear after absorption; can avoid the impact on the anti-reflux function at the junction between the ureter and urinary bladder; and can be degraded and excretedvia the urine after completion of drainage and support to avoid the secondary use of cystoscopy, and also to avoid urinary tract infections, renal dysfunction and other complications.
