Randomized Controlled Study on Acupoint Injection with BCG-polysaccharide Nucleic Acid for Bronchial Asthma
10.13460/j.issn.1005-0957.2015.06.0500
- VernacularTitle:卡介苗多糖核酸穴位注射治疗支气管哮喘随机对照试验
- Author:
Lifang CHEN
;
Luni CHEN
;
Chao WANG
;
Weirong FAN
;
Jianqiao FANG
- Publication Type:Journal Article
- Keywords:
Asthma;
Hydroacupuncture;
BCG-polysaccharide nucleic acid injection;
Randomized controlled trial
- From:
Shanghai Journal of Acupuncture and Moxibustion
2015;(6):500-502
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the clinical efficacy of acupoint injection with BCG-polysaccharide nucleic acid (BCG-PSN) in treating bronchial asthma. Method Seventy-two patients with bronchial asthma were randomized into an acupoint injection group and a muscular injection group, 36 cases in each group. The acupoint injection group was intervened by acupoint injection with BCG-PSN to Zusanli (ST36) and Dingchuan (EX-B1) alternately, 1 mL for two points in total each time; the muscular injection group was intervened by muscular injection at the same dose and frequency, twice a week, for successive 3 months. The pulmonary function and asthma control test (ACT) were estimated before and after intervention and during March of the next year. Result After intervention, the FEV1 values were (80.97±2.31)% and (80.78±2.56)% respectively in the acupoint injection group and muscular injection group, and PEF values were (6.50±0.21)L/s and (6.48±0.25)L/s, and the between-group differences were statistically insignificant (P>0.05). The ACT score was (23.02±1.03) in the acupoint injection group, significantly better than (22.40±2.04) in the muscular injection group (P<0.05). The follow-up study showed that the ACT score in the acupoint injection group was superior to that in the muscular injection group (P<0.05). Conclusion Acupoint injection and muscular injection with BCG-PSN can equally improve the pulmonary function in bronchial asthma, while the acupoint injection can produce a more significant effect than muscular injection in improving ACT.
