An Uncommon Side Effect of a Commonly Used Antibiotic: Amoxicillin-Clavulanic Acid Induced Hepatitis.
10.4082/kjfm.2017.38.5.307
- Author:
Vinay Mathew THOMAS
1
;
Neena THOMAS-EAPEN
Author Information
1. Medical College, Thiruvananthapuram, Kerala, India.
- Publication Type:Case Report
- Keywords:
Amoxicillin-Clavulanic Acid;
Hepatitis;
Hepatology;
Drug Reactions;
Jaundice;
Pruritus
- MeSH:
Amoxicillin-Potassium Clavulanate Combination*;
Diagnosis;
Female;
Gastroenterology;
Hepatitis*;
Humans;
Jaundice;
Middle Aged;
Nausea;
Pruritus;
Vomiting
- From:Korean Journal of Family Medicine
2017;38(5):307-310
- CountryRepublic of Korea
- Language:English
-
Abstract:
Amoxicillin-Clavulanic acid continues to be one of the most commonly used antibiotic combinations. Hepatic injury due to this antibiotic is rare. We report a case of amoxicillin-clavulanic acid induced hepatitis causing painless jaundice to bring to attention this rare side effect of this commonly used antibiotic. This is a case of a 62-year-old Caucasian female, who presented with acute onset severe painless jaundice, nausea, vomiting, and pruritus of less than 1-week duration. She had completed a course of amoxicillin-clavulanic acid 3 weeks prior to presentation. A careful history pointed to this simple diagnosis. It may be easily missed without an in-depth history and the patient may be subjected to unnecessary expensive tests. This case is reported to highlight cost conscious care by keeping in mind a rare side effect of the commonly used antibiotic.
