Study on quality specification of bazheng capsule
- VernacularTitle:八正胶囊的质量标准研究
- Author:
Yong CHEN
- Publication Type:Journal Article
- Keywords:
bazheng capsules;
emodin;
chrysophanol;
TLC;
content determination
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(3):179-182
- CountryChina
- Language:Chinese
-
Abstract:
Objective To improve the quality of the standard bazheng capsule.Methods TLC was used for identification of emodin and chrysophanol content determination, and determination of samples by high performance liquid chromatography.Results TLC spots were clear,and the blank without interference.Emodin showed a good linear relationship at range of 0.0267 ~0.4272 μg, Y =1425.7X +2.1521 ( r=0.9998 );chrysophanol showed a good linear relationship at range of 0.0417 ~0.6677 μg, Y =5 ×106X -8566.2(r=0.9999).The recovery was 97.35%, 98.39%,and RSD was 1.7%,0.4%.Conclusion The established methods are simple and with good repeatability, and can be used for the quality control of bazheng capluse.
