The Predictive Value of Fractional Flow Reserve Level for Long-term Prognosis in Patients After Coronary Drug-eluting Stent Implantation
10.3969/j.issn.1000-3614.2015.07.003
- VernacularTitle:冠状动脉药物洗脱支架置入后血流储备分数对患者远期预后的预测价值
- Author:
Xuebiao WEI
;
Xing YANG
;
Demou LUO
;
Lei JIANG
;
Jiaxin ZHAN
;
Junqing YANG
;
Danqing YU
- Publication Type:Journal Article
- Keywords:
Fractional lfow reserve;
Stent;
Prognosis
- From:
Chinese Circulation Journal
2015;(7):627-630
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the predictive value of fractional lfow reserve (FFR) level for long-term prognosis in patients after coronary drug-eluting stent (DES) implantation, and to analyze the relevant factors affecting the level of post-operative FFR. Methods: A total of 135 patients who received DES implantation in our hospital from 2012-01 to 2013-07 with coronary intermediate lesion at (50-80) % were studied. The relevant factors for MACE occurrence were studied by multivariate logistic regression analysis, the post-stent FFR level for predicting the long term prognosis after DES implantation was ifnally analyzed by ROC curve. Results: All patients ifnished 1 year follow-up study including 104 male and 31 female with the mean age of (63 ± 9) years. The post-stent FFR level was lower in MACE group than that in Non-MACE group, (0.82 ± 0.07) vs (0.87 ± 0.06),P=0.004. Multivariate logistic regression analysis presented that the higher level of post-stent FFR was the protective factor for MACE occurrence (OR=0.212,P=0.039); the post-stent FFR level had certain predictive value for MACE occurrence at 1 year after DES implantation (AUC=0.706,P=0.006); Kaplan-Meier survival study showed that the patients with post-stent FFR<0.875 had the less MACE occurrence than those with FFR≥0.875,P=0.012. Multivariate logistic regression analysis also indicated that post-stent FFR≥0.875 was positively related to right coronary target vessel, higher pre-operative FFR level and larger stent diameter.Conclusion: Post-stent FFR level had certain predictive value for MACE occurrence in patients at 1 year after DES implantation, the patients with post-stent FFR≥0.875 had the lower MACE occurrence rate than those with FFR<0.875.
