A Case of Papular Acantholytic Dyskeratosis Treated with Carbon Dioxide Laser.
- Author:
Soo Kyung LEE
1
;
Dong Joo KIM
;
Joong Heon SUH
;
Un Ha LEE
;
Myoung Shin KIM
Author Information
1. Department of Dermatology, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea. etihwevol@naver.com
- Publication Type:Case Report
- Keywords:
Papular acantholytic dyskeratosis;
Acantholytic dermatosis;
Perianal area
- MeSH:
Acantholysis;
Biopsy;
Carbon Dioxide*;
Carbon*;
Darier Disease;
Diagnosis, Differential;
Epidermis;
Humans;
Incidence;
Lasers, Gas*;
Middle Aged;
Pemphigus, Benign Familial;
Skin
- From:Korean Journal of Dermatology
2017;55(8):518-521
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Papular acantholytic dyskeratosis is a collection of papular skin lesions that occur in the intertriginous and genital area. They show a characteristic histology of focal suprabasal acantholysis that distinguishes it from Hailey-Hailey disease or Darier disease. We describe a 50-year-old man with an asymptomatic papular eruption on the perianal area for several years. Histologically, a biopsy specimen showed diffuse hyperkeratosis and irregular acantholysis throughout the epidermis. We used carbon dioxide laser therapy as a therapeutic option. Despite causing a long and painful healing process, a considerable reduction of the symptoms was achieved. Although we do not know the precise nature or the incidence of this disease, papular acantholytic dyskeratosis should be included in the differential diagnosis of verrucous papules in perineal or perianal areas and carbon dioxide laser may represent a good therapeutic option.
