Clinical Study onXiaozhikang Formula Granules for the Treatment of Nonalcoholic Fatty Liver Disease
10.3969/j.issn.1005-5304.2015.08.007
- VernacularTitle:消脂康配方颗粒治疗非酒精性脂肪肝临床研究
- Author:
Shijie LI
;
Hongwei ZHAI
- Publication Type:Journal Article
- Keywords:
Xiaozhikang Formula Granules;
nonalcoholic fatty liver disease;
clinical efficacy
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2015;22(8):22-25
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy ofXiaozhikang Formula Granules for the treatment of nonalcoholic fatty liver disease.Methods Totally 90 patients with nonalcoholic fatty liver disease were randomly divided into control group and treatment group, 45 cases in each group. Patients in the control group were treated with conventional western treatment and oral metformin enteric-coated metformin hydrochloride, while patients in the treatment group were treated withXiaozhikang Formula Granules on the basis of conventional western treatment for 3 months. Blood lipid and insulin resistance in the two groups before and after treatment were observed, and the clinical efficacy between the two groups was compared.Results Clinical excellence (35.5%), total effective rate (84.5%) and TCM syndrome score (13.78 ± 3.6) after treatment of treatment group were better than those of control group (P<0.05). GPT, GOT, TG, and TC in both groups were lower after the treatment (P<0.05,P<0.01). There existed statistical significance in TC and TG between the two groups after treatment (P<0.05). There existed statistical significance in B ultrasound index between the two groups after treatment (P<0.05), and the treatment group was superior. FBG and HOMA-IR in both groups significantly decreased after treatment (P<0.05), and the FBG in the treatment group after treatment was better than control group (P<0.05).Conclusion The efficacy ofXiaozhikang Formula Granules in the treatment of nonalcoholic fatty liver disease is remarkable.
