Antitumor effects of metformin
10.3760/cma.j.issn.1673-422X.2015.04.011
- VernacularTitle:二甲双胍的抗肿瘤作用
- Author:
Yanxun GUO
;
Shiyin MA
- Publication Type:Journal Article
- Keywords:
Metformin;
Neoplasms;
Antitumor
- From:
Journal of International Oncology
2015;(4):281-283
- CountryChina
- Language:Chinese
-
Abstract:
Metformin as a cheap,safe and effective diabetes drug,has been used for many years. Recently,many studies have shown its variety inhibition of tumor cells. Its antitumor mechanism is not entirely clear;may be related to glucose metabolism and protein kinase or inflammatory cytokines mediating tumor kill-ing. Metformin has different cytotoxic effects to various tumor cell,as well as playing some auxiliary roles on other antitumor methods.
