Combined cognitive rehabilitation training on treating cognitive function disorder caused by amphetamine-type stimulant:A randomised controlled study
10.3969/j.issn.1000-6729.2015.07.009
- VernacularTitle:认知康复综合训练改善苯丙胺类依赖者认知功能的随机对照试验
- Author:
Chuanwei LI
;
Haifeng JIANG
;
Ding XU
;
Feng QIAN
;
Wei ZHANG
;
Jiang DU
;
Yan ZHAO
;
Min ZHAO
- Publication Type:Journal Article
- Keywords:
amphetamine-type stimulants;
combined cognitive rehabilitation training;
cognitive function;
clinical trials
- From:
Chinese Mental Health Journal
2015;(7):528-532
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To assess the effect of combined cognitive rehabilitation training on improving cogni-tive dysfunction in amphetamine-type stimulant dependent patients.Methods:Subjects who met the clinical diagno-sis of ATS dependence by DSM-IV in compulsory isolation detoxification institute were randomly assigned into in-tervention group (n =30 )and control group (n =26 ).Control group received a regular education.Intervention group also received a combined cognitive rehabilitation training besides regular education,including psychological and physical rehabilitation for 24 weeks.The Chinese version of CogState Battery (CSB)was used to assess cogni-tive function at baseline and 24 weeks after the intervention.Results:No significant difference was found on all sub-scales scores of CogState Battery between two groups at baseline.At 24 weeks after the intervention,compared to control group,the intervention group had more improvements in three sub-scale scores,i.e.,One Card LearningTask [(0.06 ±0.12)vs. (-0.03 ±0.14),P<0.05],Two-back Task [(0.12 ±0.15)vs. (0.01 ±0.19),P<0.05]and Continuous Paired Association Learning Task [(-0.46 ±0.35)vs. (-0.15 ±0.49),P<0.05].No difference was found on improvements in the rest 5 sub-scale scores,i.e.,Detection Task,Identification Task,Inter-national Shopping List Task,Groton Maze Learning Task and Social Emotional Cognition Task (P >0.05 ).Conclusion:The combined cognitive rehabilitation training could improve amphetamine-type stimulant dependent patients'visual learning and memory,working memory and spatial working memory,while have no significant im-provement on other cognitive functions.
