Distribution and drug resistance change of common pathogenic bacteria in hospital
10.3969/j.issn.1673-4130.2015.08.007
- VernacularTitle:医院常见病原菌的分布及耐药性变迁
- Author:
Lingli GU
- Publication Type:Journal Article
- Keywords:
common pathogens;
distribution;
surveillance of bacterial resistance
- From:
International Journal of Laboratory Medicine
2015;(8):1028-1031
- CountryChina
- Language:Chinese
-
Abstract:
Objective To understand the constituent ratio and the drug resistance tendency of the common pathogens in hospital in order to provide the basis for rational clinical drug use and control of nosocomial infection .Methods The pathogenic bacteria iso‐lated from the various submitted clinical specimens and their drug resistance in our hospital from January 2012 to December 2014 were performed the retrospective analysis .Results A total of 1 325 strains of pathogenic bacteria were isolated ,among them 889 strains (67 .10% ) were Gram‐negative cocci ,284 strains(21 .43% ) were Gram‐positive cocci and 152 strains (11 .47% ) were fun‐gi .The top five of isolated strains were Escherichia coli ,Klebsiella pneumonia ,Pseudomonas aeruginos ,Staphyloccocus aureus and Acinetobacter baumannii .Escherichia coli and Klebsiella pneumonia were highly resistant to imipenem with the resistance rate of 3 .7% ,but carbapenems‐resistant strain(CRE) was detected out .The resistant rateof Pseudomonas aeruginos to meropenem was in‐creased and which to imipenem was decreased .The resistant rates of Acinetobacter baumannii to meropenem and imipenem were o‐ver 44 .83% .The detection rate of methicillin‐resistant Staphylococcus aureus (MRSA ) was decreased from 69 .05% to 54 .05% . Enterococcus faecium was highly sensitive to vancomycin ,linezolid ,teicoplanin and furadantin .But vacomycin‐resistant strains (VRE) were found .Conclusion The drug resistance of common pathogens causing nosocomial infection is serious in our hospital . Therefore ,it is very important to strengthen the monitoring of bacterial drug resistance ,rationally use antimicrobial drugs and adopt the effective measure of infection control to prevent and reduce the generation of drug‐resistant pathogens .
