Effects of exercise on spleen T lymphocyte proliferation and T-lymphocyte subsets of SD rats
10.3969/j.issn.1000-484X.2015.04.009
- VernacularTitle:运动对大鼠脾脏T淋巴细胞增殖及T细胞亚群的影响研究
- Author:
Jian NIE
;
Jihan WANG
- Publication Type:Journal Article
- Keywords:
Exercise;
Immune function;
T lymphocyte proliferation;
T lymphocyte subsets
- From:
Chinese Journal of Immunology
2015;(4):477-479
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effects of exercise on the spleen T lymphocyte proliferation and T lymphocyte subsets of SD rats.Methods:24 SD rats were divided into 3 groups randomly:control group,30 min exercise group,60 min exercise group;MTT and flow cytometry ( FCM ) were utilized to examine the spleen T lymphocyte proliferative capability and T lymphocyte subsets, respectively.Results:Compared with the control group,the T lymphocyte proliferation,levels of CD4+and CD4+/CD8+T lymphocytes in 30 min exercise group rats were significantly increased(P<0.05),levels of CD8+T lymphocytes in 30 min exercise group rats had no statistically significant change;the T lymphocyte proliferation,levels of CD4+,CD8+and CD4+/CD8+T lymphocytes in 60 min exercise group rats had no statistically significant changes.Conclusion: Suitable loaded exercise could enhance the cellular immune function, this is probably related with the mechanisms of improving the T lymphocyte proliferative capability and regulating the CD4+/CD8+T lymphocyte subsets.
