A case of melanotic neuroectodermal tumor of infancy and review of literature
- VernacularTitle:婴儿色素性神经外胚层瘤1例并文献复习
- Author:
Jingjing MAO
;
Xingqiao XU
;
Yanliang WANG
;
Zhihui ZHOU
;
Miaojie LANG
- Publication Type:Journal Article
- Keywords:
Infant;
Maxilla;
Melanotic neuroectodermal tumor ofinfancy(MNTI);
Immunohistochemistry
- From:
Journal of Practical Stomatology
2015;(4):584-587
- CountryChina
- Language:Chinese
-
Abstract:
This paper reports a case of melanotic neuroectodermal tumor of infancy (MNTI)arising in the maxilla of a 3-month-old male infant.The treatment included surgical excision of the lesion with safe margin,curettage of the maxilla and removal of associated developing tooth bud.Microscopically,it proved to be a dual tumor with small,neuroblastic-like cells and larger epithelial cells.Immunohistochemical staining demonstrated epitheloid cells HMB45(+),EMA(+),CK(+);neuroblast-like cells NSE(+),GFAP(+),S-100(+),but both cells Vim(+),CD45(-),Myogenin(-).The 18-mouth follow-up showed no recurrence or metastasis.The related literature was re-viewed.