Comparison on Pomegranate Leaf Tennis andAnanas coumosus Leaf Phenols on Growth of Lactation Mice
10.11842/wst.2015.03.018
- VernacularTitle:石榴叶鞣质与菠萝叶酚对哺乳期小鼠生长的比较
- Author:
Xinpei WANG
;
Dongming XING
;
Jingfei JIANG
;
Xuan YU
;
Xiaojin YAN
;
Fan LEI
;
Lijun DU
- Publication Type:Journal Article
- Keywords:
Pomegranate leaf;
Ananas coumosus leaf;
mouse;
growth and development;
lactation
- From:
World Science and Technology-Modernization of Traditional Chinese Medicine
2015;17(3):526-530
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to observe the effect ofpomegranate leaf tennis and Ananas coumosus leaf phenols on the growth of lactating mice through breast milk. Intragastric administration of different doses of drug was given to maternal mice. The general condition of newborn mice, body weight, tail length and organ coefficient of liver-related factors regulating the expression of lipid metabolism were observed. The results showed that both pomegranate leaf tennis and A. coumosus leaf phenols can obviously affect the growth and development of newborn mice through breast milk. And the effect of pomegranate leaf tennis was stronger than A. coumosus leaf phenols. Meanwhile, it obviously downregulated the expression of liver-related lipid metabolism enzymes in newborn mice. It was concluded that pomegranate leaf tennis and A. coumosus leaf phenols can affect the growth and development of newborn mice through breast milk. Its effect was related to the influence of lipid metabolism enzyme in the liver. Attention should be paid on taking this medication during lactation. Its clinical significance still required in-depth study.
