Significance of pre-B cell colony enhancing factor in diagnosis and treatment of neonatal sepsis
10.3760/cma.j.issn.2095-428X.2015.10.020
- VernacularTitle:前B细胞集落增强因子对新生儿脓毒症诊疗的意义
- Author:
Weibin WU
;
Weimin HUANG
- Publication Type:Journal Article
- Keywords:
Neonatal sepsis;
Pre-B cell colony enhancing factor;
Gene polymorphism;
Biomarker
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;30(10):787-789
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis is still a major cause of death among neonates and its morbidity rate remain high nowadays.Because of the atypical symptoms and extremely dangerous progress in neonatal sepsis,early diagnosis and treatment are requisite.But the unique biomarkers are lacking meanwhile.Recent study shows that PBEF influences individual susceptibility,severity and outcome in sepsis.This review synthesizes the research of PBEF in neonatal sepsis in order to provide the evidence of reliable biomarker to diagnose and treat neonatal sepsis in the early stage.
