Advances in Study on Liver Regeneration
10.3969/j.issn.1008-7125.2015.03.008
- VernacularTitle:肝再生研究进展
- Author:
Renxin FENG
;
Xing DENG
;
Xin ZHANG
;
Weifen XIE
- Publication Type:Journal Article
- Keywords:
Liver Regeneration;
Hepatocytes;
Hepatic Progenitor Cells;
Hepatic Stellate Cells;
Liver Sinusoidal Endothelial Cells
- From:
Chinese Journal of Gastroenterology
2015;(3):169-173
- CountryChina
- Language:Chinese
-
Abstract:
One of the most important characteristics of adult liver is its regenerative ability to maintain its original mass and function after injury. With remarkable self-replication ability, hepatocytes play a critical role in liver regeneration. When there is a restriction in the proliferation capacity and/ or a massive loss of mature hepatocytes,other cells in liver can contribute to liver regeneration in different ways. Deep study on the effects and mechanisms of various hepatic cells’contribution to liver regeneration is helpful for increasing the understanding about liver regeneration and providing new insights for diagnosis and management of various advanced liver diseases.