Effects of changing temporal resolution of spiral computed tomography on perfusion of cervical cancer and radiation dose
10.7652/jdyxb201503020
- VernacularTitle:改变时间分辨力对宫颈癌螺旋 CT 灌注及辐射剂量的影响
- Author:
Zhendong CAO
;
Shenglin WANG
;
Chunhui LI
;
Shuxian WANG
;
Fengchun LIU
;
Xue SONG
;
Limei JIA
- Publication Type:Journal Article
- Keywords:
cervical cancer;
temporal resolution;
perfusion;
time density curve;
mathematical model;
compu-ted tomography(CT);
radiation dose
- From:
Journal of Xi'an Jiaotong University(Medical Sciences)
2015;(3):387-390
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of different temporal resolution of spiral computed tomography (CT)on perfusion parameters and perfusion curve of cervical cervical cancer.Methods Ten cases of cervical cancer were clinically confirmed with CT perfusion scanning.The original data were acquired using temporal resolution of 0.75 s.Then the original data were grouped according to different temporal resolution,namely,1.5 s group,2.25 s group,3 s group,3.75 s group,4.5 s group,5.25 s group,and 6 s group (experiment group). According to the same mathematical model and ROI of the same part,perfusion parameters (BF,BV,MTT,and PS)in each group were calculated respectively and compared with the original data.Results BF and MTT were relatively sensitive to the change of temporal resolution.When the temporal resolution was 3 s,it had a significant impact.PS and BV were not so sensitive to the change of temporal resolution.Temporal resolution of 4.5 s had a significant effect on PS. There was a significant effect on BV until the temporal resolution was 5.25 s. Conclusion Changing the temporal resolution will lead to corresponding changes of perfusion curve and perfusion parameters.Under the premise that it does not affect the diagnosis,properly decreasing temporal resolution (circu-lar scanning temporal ≤2.25 s)of CT perfusion scanning of cervical cancer can reduce the radiation dose effectively.
