Influence of type 2 diabetes mellitus on coronary artery lesion and plaque using optical coherence tomo- graphy in patients with coronary artery disease
10.3969/j.issn.1008-0074.2015.02.15
- VernacularTitle:应用光学相干断层成像评估糖尿病对冠心病冠脉病变及斑块的研究
- Author:
Xuan GAO
;
Chunfeng NIU
;
Bo YU
- Publication Type:Journal Article
- Keywords:
Coronary disease;
Tomography,optical coherence;
Diabetes mellitus,type 2
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2015;24(2):168-172
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study influence of type 2 diabetes mellitus (T2DM) on coronary artery lesion and plaque sta‐bility using optical coherence tomography (OCT) in patients with coronary artery disease (CAD) manifesting unsta‐ble angina pectoris (UAP) . Methods :A total of 200 patients diagnosed as CAD manifesting UAP were selected.According to complicated with diabetes mellitus or not ,they were divided into normal blood glucose group (n=98) and complicated T2DM group (T2DM group ,n=102). Coronary angiography (CAG) and OCT were used to eval‐uate coronary artery lesion ,assess plaque nature and measure the thickness of plaque fibrous cap in order to confirm plaque stability . Results:Compared with normal blood glucose group ,there were significant rise in percentages of multi-vessel coronary disease (48.98% vs. 78.43% ) ,severe artery stenosis (20.57% vs. 40.21% ) ,lipid plaques (25.00% vs. 39.84% ) and plaques with fibrous cap thickness <65μm (25.93% vs. 45.24% ) in T2DM group , P<0.05 or < 0.01 .Conclusion :Patients with coronary artery disease have more severe coronary artery lesion and high ‐ er incidence rate of multi‐vessel coronary disease and unstable plaque when complicated with type 2 diabetes mellitus .
