Regulation and mechanism of microRNAs on transplanted bone marrow mesenchymal stem cell treating myocardial infarction
10.3969/j.issn.1008-0074.2015.02.28
- VernacularTitle:MicroRNAs 对骨髓间充质干细胞移植治疗心肌梗死的调控作用与机制
- Author:
Jiang RUI
;
Lü BO
;
Xu WEI
;
Yu BO
- Publication Type:Journal Article
- Keywords:
MicroRNA;
Myeloid progenitor cells;
Myocardial infarction
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2015;24(2):210-213
- CountryChina
- Language:Chinese
-
Abstract:
Current researches indicate that transplanted BM‐MSCs accompanies massive death ,and its effect is unsat‐isfactory .The miRNAs are a class of small non‐coding single‐stranded RNA molecules ,involve therapeutic course of bone marrow mesenchymal stem cell treating myocardial infarction in many respects .The present article made an o‐verview on effect of microRNAs in transplanted BM‐MSCs treating myocardial infarction via mainly illustrating bio‐logical function of microRNAs and its regulation effect on BM‐MSCs differentiation and paracrine secretion .
