Application Analysis of Total Parenteral Nutrition Use in Neonatal Units
10.3870/yydb.2015.04.034
- VernacularTitle:新生儿科全肠外营养液的应用分析
- Author:
Yubo ZHUO
;
Lianfang XUE
;
Yifei WANG
- Publication Type:Journal Article
- Keywords:
Total parenteral nutrition;
Preterm infant;
Prescription analysis;
Rationality
- From:
Herald of Medicine
2015;(4):538-541
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate how total parenteral nutrition( TPN) is applied in the neonatal units of the first affiliated hospital of Jinan university, provide reference for the standardized use of TPN, formulate appropriate guidelines, and ensure that clinical nutrition is properly and safely used in prenatal patients. Methods Preterm infants with gestational age<37 weeks and birth weights <2 500 g who used TPN in the neonatal units from January 2012 to June 2013 were assigned into two groups, Patients in Group 1 (n=27) began TPN within 3 d after birth, and patients in Group 2 (n=28) began TPN 3 d after birth. Body weight and the time to regain birth weight were obtained at discharge,, and biochemical indexes before and after TPN were also evaluated. Results Compared with late TPN, early TPN significantly reduce the time to regain birth weight[(12. 5± 7. 2) d vs (8. 9±5. 5) d, P<0. 05], and maintained normal blood glucose level (P<0. 05). There were no differences with regards to length of hospitalization, duration of TPN use, growth rate, blood glucose, K+, Ca2+, Cl-, BUN, serum creatinine, BUN and serum bilirubin (all P>0. 05). Both groups can effectively prevent and correct hypoglycemia and hypocalcemia. Conclusion Early TPN can promote growth of preterm infant. The use of TPN can improve hypoglycemia and hypocalcemia without effect on liver and kidney function. Neither group achieved ideal nutritional support outcome and therefore requires further improvement.
