Progress of behavioral tests in rat models of Parkinson’ s disease
10.3969/j.issn.1005-4847.2015.02.020
- VernacularTitle:帕金森病大鼠模型运动行为测评方法的研究进展
- Author:
Xiang WEI
;
Xiaoli LIU
- Publication Type:Journal Article
- Keywords:
Parkinson’ s disease;
Rat;
Motor function;
Behavioral tests
- From:
Acta Laboratorium Animalis Scientia Sinica
2015;(2):209-215
- CountryChina
- Language:Chinese
-
Abstract:
Parkinson’ s disease ( PD) is a neurodegenerative disorder primarily characterized by resting tremor, muscular rigidity, akinesia and postural reflex impairment.Behavioral tests of PD in animal models are essential for under-standing the pathogenesis of PD as well as for the development and testing of potential therapeutics .Here we mainly use the 6-hydroxydopamine (6-OHDA)-induced rat model, to introduce a review on the research progress in non-drug-induced be-havioral tests of motor function in PD rats.
