New progress in animal models of osteosarcoma
10.3969/j.issn.1005-4847.2015.02.021
- VernacularTitle:骨肉瘤动物模型新进展
- Author:
Cegang FU
;
Hongwei ZHAO
;
Yang LIU
;
Lujiao HE
;
Mengxi HE
;
Haidan CHEN
- Publication Type:Journal Article
- Keywords:
Osteosarcoma;
Animal;
Models
- From:
Acta Laboratorium Animalis Scientia Sinica
2015;(2):216-220
- CountryChina
- Language:Chinese
-
Abstract:
Osteosarcoma ( OS) is the most common primary malignant bone tumor in children and adolescents. Currently, the combination of surgical resection and chemotherapy is the main method of treatment for OS in the clinic.Al-though, the survival rate has been greatly improved in OS patients with localized disease, the 5-year survival rate has re-mained <20%.It is very important to understand the cause of disease, to develop novel drugs or therapeutics, and to learn the disease through animal models.This review will introduce the progress of animal models of osteosarcoma over the last years.