Intracranial tumor in children:a clinicopathological analysis of 221 cases

VernacularTitle:儿童颅内肿瘤221例临床病理分析
Author: Xuefeng TANG ; Yingqin KONG ; Qiaonan GUO
Publication Type:Journal Article
Keywords: intracranial neoplasm; children; clinicopathological analysis
From: Chinese Journal of Clinical and Experimental Pathology 2015;(3):298-301
CountryChina
Language:Chinese
Abstract: Purpose To analyze the clinical and pathological features of intracranial tumor in children. Methods 221 cases of in-tracranial tumors in children ( ages≤18 years) were retrospectively analyzed. Results The cases of intracranial tumor in children ac-counted for 7. 21% of total cases in our hospital during the same period. There is no documented gender bias. There were only 14 cases (6. 33%) with age less than 3 years old. The supratentorial tumors were 153 cases (69. 23%) and infratentorial tumors were 68 cases (30. 77%) . The most frequently affected sites were the cerebral hemispherse, sellar region, vermis and the fourth ventricle. There were 89 benign tumor and 132 malignant tumor in this series of cases. The most common five tumors were astrocytic tumors (30. 32%), embryonal tumors (19. 00%), craniopharyngiomas (11. 76%), ependymal tumors (8. 14%) and germ cell tumors (5. 88%). Conclusion The morbidity of intracranial tumors in children has increased in the recent years. The histological classifica-tion of intracranial tumors in children is multiple and it is essential to make a correct diagnosis.