Research progress of miRNA expression in kidney disease
10.3969/j.issn.1000-3606.2015.04.023
- VernacularTitle:miRNA表达在肾脏病中应用的研究进展
- Author:
Pei ZHANG
;
Zhengkun XIA
;
Chunlin GAO
- Publication Type:Journal Article
- Keywords:
miRNA;
diabetic nephropathy;
focal segmental glomerulosclerosis;
IgA nephropathy;
lupus nephritis
- From:
Journal of Clinical Pediatrics
2015;(4):383-386
- CountryChina
- Language:Chinese
-
Abstract:
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression at the post-transcriptional lev-el and then affect important physiological and pathological processes. Many microRNAs are tissue or organ-speciifc which make it possible for them to become potential biomarkers. Similarly, microRNAs are important for physiological functions of kidney and they are involved in various renal disorders. The review summarizes current information about microRNA effect on various kidney diseases, in order to provide references for the diagnosis and treatment of kidney disease in the future.
