Progress in non-invasive ventilation for the treatment of neonatal respiratory disease

VernacularTitle:无创通气在治疗新生儿呼吸系统疾病中的应用进展
Author: Xindan ZHANG ; Jun ZHENG ; Xiaopeng WANG ; Junling MA
Publication Type:Journal Article
Keywords: non-invasive ventilation; continuous positive airway pressure; nasal intermittent positive pressure ventila-tion; neonatal respiratory distress syndrome; bronchopulmonary dysplasia
From: Journal of Clinical Pediatrics 2015;(4):387-390
CountryChina
Language:Chinese
Abstract: Mechanicalventilation in newborns can be divided into invasive mechanical ventilation and non-invasive me-chanical ventilation. In order to reduce invasive ventilation-induced lung injury, more and more non-invasive ventilation patterns have been used clinically. Early application of nasal intermittent positive pressure ventilation (NIPPV) has become the main mode of non-invasive ventilation in many neonatal intensive care units (NICU). At the same time, the combination with selective pulmonary surfactant can reduce the incidence of chronic lung disease. This article reviews the use and prospect of non-invasive respiratory support modes which include continuous positive airway pressure (CPAP) and bi-level CPAP mode (BiPAP) such as SiPAP and NIPPV. Some modes which are in the research stage were also reviewed including synchronized nasal intermittent positive pressure ventilation, neurally adjusted ventilatory assist and non-invasive high-frequency oscillatory ventilation.