Predictive value of random spot albuminuria to creatinine ratio in women with hypertensive disorders complicating pregnancy

VernacularTitle:随机尿白蛋白／肌酐比值对妊娠期高血压疾病的预测价值
Author: Hong YIN ; Yunfei GAO ; Shuming HE ; Yanping YU ; Qitao HUANG ; Yan WANG ; Zijing KONG ; Mei ZHONG
Publication Type:Journal Article
Keywords: Hypertension; Pregnancy-Induced; Albuminuria; Creatinine,Urinalysis
From: The Journal of Practical Medicine 2015;(9):1441-1443
CountryChina
Language:Chinese
Abstract: Objective To determine the random spot albuminuria to creatinine ratio (ACR) of normal pregnant women , to track the pregnancy outcome , and to discuss the predictive value of ACR in women with hy-pertensive disorders complicating pregnancy (HDCP). Methods Except for 87 pregnant women suffering from HDCP, 2 038 pregnant women were enrolled in this study. ACR, routine examinations of blood and urine, blood biochemical, 24-hr urinary protein were determined. Results ACR, but not 24-hr urinary protein level,was sig-nificantly higher in women with HDCP. There was positive correlation between the ACR and 24-hr urinary protein quantitation. Age, gestational weeks, ACR, red blood cells, fasting plasma glucose, serum creatinine, total pro-tein were the independent risk factors for HDCP. The sensitivity , specificity and optimal cut off value of ACR for predicting HDCP were 0.78, 0.63, 1.46 mg/mmol. Conclusions There was positive correlation between ACR and 24-hr urinary protein quantitation , and ACR provided a more sensitive pathway for early predictionof HDCP.