Ubiquitin-Conjugating EnzymeE2C and tumors
- VernacularTitle:泛素结合酶E2C与肿瘤的关系研究进展
- Author:
Shaobing WANG
;
Fang WANG
- Publication Type:Journal Article
- Keywords:
Ubiquitin-conjugating enzyme;
Ubiquitin-conjugating EnzymeE2C;
Mitosis;
Cancer
- From:
Journal of Medical Postgraduates
2015;(5):543-548
- CountryChina
- Language:Chinese
-
Abstract:
More and more evidences have shown that disorder of ubiquitination regulates the genesis and development of tumors.Ubiquitin-conjugating enzymeE2C(UBE2C), an important member of Ubiquitin-Conjugating Enzyme family, is the key factor for metaphase-metaphase transition regulation .In recent years , many studies have focused on the relationship between UBE2 C and tumors .This article reviews the progress of UBE2C expression status in tumors, its influence on genesis and development of tumors and the underlying mechanism .
